Edit |   |
---|---|
Antigenic Specificity | RPS6KA4 (C-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This RPS6KA4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 720-754 amino acids from the C-terminal region of human RPS6KA4. Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factor RELA, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. Plays an essential role in the control of RELA transcriptional activity in response to TNF. Phosphorylates 'Ser |
Immunogen | n/a |
Other Names | [Ribosomal protein S6 kinase alpha-4; S6K-alpha-4; 90 kDa ribosomal protein S6 kinase 4; Nuclear mitogen- and stress-activated protein kinase 2; Ribosomal protein kinase B; RSKB; RPS6KA4; MSK2] |
Gene, Accession # | [RPS6KA4], Gene ID: 8986, NCBI: NP_001006945.1, UniProt: O75676 |
Catalog # | MBS9207888 |
Price | $165, $370 |
Order / More Info | RPS6KA4 (C-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Pierrat B.,et al.J. Biol. Chem. 273:29661-29671(1998). Ota T.,et al.Nat. Genet. 36:40-45(2004). Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases. Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. Deak M.,et al.EMBO J. 17:4426-4441(1998). |