Human CD80 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD80
Clone[4A2D10.4]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatfluorescein (FITC) conjugate
Size50 tests, 100 tests
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF)
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DescriptionCD80, also known as B7-1, B7, and BB1, is a 60 kD single chain type I glycoprotein belonging to the immunoglobulin superfamily. CD80 is expressed on activated B and T cells, macrophages, and dendritic cells. CD80 binds to CD28 and CD152 (CTLA-4). Along with CD86, CD80 plays a critical role in regulation of T cell activation. The interaction of CD80 with CD28 provides a potent costimulatory signal for T cell activation through the CD3 complex, while its interaction with CTLA-4 provides an inhibitory signal for T cell activation.
Immunogenn/a
Other Names[T-lymphocyte activation antigen CD80; T-lymphocyte activation antigen CD80; CD80 molecule]
Gene, Accession #[CD80], Gene ID: 768950, NCBI: NP_001073207.1
Catalog #MBS8502756
Price$215, $280
Order / More InfoHuman CD80 Antibody from MYBIOSOURCE INC.
Product Specific References1. You CX et al., (2012) Oncoimmunology 1(6):847-855. 2. Gibbons RM et al., (2012) Oncoimmunology 1(7):1061-1073. 3. Garufi A et al., (2012) PLoS One 7(11):e48342.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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