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Antigenic Specificity | Trail |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | ion exchange purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Trail Antibody: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel member in the TNF family was recently identified and designated TRAIL (for TNF-related apoptosis-inducing ligand) and Apo-2L (for Apo-2 ligand)1, TRAIL is a type II membrane protein and expressed in a variety of human tissues. Two novel death domain containing receptors DR4 and DR5 have been identified as the receptor for TRAIL3-6. Like TNF and Fas ligand, TRAIL induces apoptosis and NF-κB activation in many tissues and cells. |
Immunogen | Immunogen: TRAIL antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human TRAIL. Buffer: Trail Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [Trail; TL2; APO2L; CD253; TRAIL; Apo-2L; Tumor necrosis factor ligand superfamily member 10; Apo-2 ligand; tumor necrosis factor (ligand) superfamily, member 10], [TNFSF10; TNFSF10; TL2; APO2L; CD253; TRAIL; Apo-2L; APO2L; TRAIL; Apo-2L; Protein TRAIL] |
Gene, Accession # | [TNFSF10], Gene ID: 8743, NCBI: NP_003801, UniProt: P50591 |
Catalog # | MBS150492 |
Price | $375 |
Order / More Info | Trail Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |