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Antigenic Specificity | DAPK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell death signals, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation (PubMed:17347302). Regulates granulocytic motility by controlling cell spreading and polarization (PubMed:24163421). |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human DAPK2 (NP 055141.2). |
Other Names | [DRP1; DRP-1] |
Gene, Accession # | [DAPK2], Gene ID: 23604, NCBI: NP_055141.2, UniProt: Q9UIK4 |
Catalog # | MBS8547290 |
Price | $280 |
Order / More Info | DAPK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |