Human DAXX Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman DAXX
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat
Isotypen/a
Formatunconjugated
Size0.05 mg
ConcentrationIgG concentration 1.0mg/ml
ApplicationsELISA (EIA), Immunohistology Paraffin*, Western Blot (WB)
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DescriptionThis item recognises human Death Domain-Associated Protein 6, a novel Fas binding protein that has been designated DAXX. . . DAXX binds specifically to the death domain of Fas and enhances Fas induced apoptosis and activates the Jun N-terminal kinase (JNK) pathway. . . DAXX is predominantly a nuclear protein, where it acts as a repressor of EtsI and Pax3 transactivation. When in association with ASK1 kinase DAXX translocates from the nucleus to the cytoplasm. MBS222885 recognises human Death Domain-Associated Protein 6, a novel Fas binding protein that has been designated DAXX. DAXX binds specifically to the death domain of Fas and enhances Fas induced apoptosis and activates the Jun N-terminal kinase (JNK) pathway. DAXX is predominantl
ImmunogenImmunogen: Synthetic peptide corresponding to amino acids 261-274 of human DAXX protein. Histology Positive Control Tissue: Human kidney Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antiserum to human DAXX was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. Target Species: Human
Other Names[death domain-associated protein 6 isoform a; Death domain-associated protein 6; death domain-associated protein 6; CENP-C binding protein; ETS1-associated protein 1; Fas-binding protein; death-associated protein 6; fas death domain-associated protein; death-domain associated protein; Daxx; hDaxx; ETS1-associated protein 1; EAP1; Fas death domain-associated protein], [DAXX; DAXX; DAP6; EAP1; BING2; BING2; DAP6; hDaxx; EAP1]
Gene, Accession #[DAXX], Gene ID: 1616, NCBI: NP_001135441.1, UniProt: Q9UER7
Catalog #MBS222885
Price$550
Order / More InfoHuman DAXX Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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