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Antigenic Specificity | Human DAXX |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | ELISA (EIA), Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item recognises human Death Domain-Associated Protein 6, a novel Fas binding protein that has been designated DAXX. . . DAXX binds specifically to the death domain of Fas and enhances Fas induced apoptosis and activates the Jun N-terminal kinase (JNK) pathway. . . DAXX is predominantly a nuclear protein, where it acts as a repressor of EtsI and Pax3 transactivation. When in association with ASK1 kinase DAXX translocates from the nucleus to the cytoplasm. MBS222885 recognises human Death Domain-Associated Protein 6, a novel Fas binding protein that has been designated DAXX. DAXX binds specifically to the death domain of Fas and enhances Fas induced apoptosis and activates the Jun N-terminal kinase (JNK) pathway. DAXX is predominantl |
Immunogen | Immunogen: Synthetic peptide corresponding to amino acids 261-274 of human DAXX protein. Histology Positive Control Tissue: Human kidney Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antiserum to human DAXX was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. Target Species: Human |
Other Names | [death domain-associated protein 6 isoform a; Death domain-associated protein 6; death domain-associated protein 6; CENP-C binding protein; ETS1-associated protein 1; Fas-binding protein; death-associated protein 6; fas death domain-associated protein; death-domain associated protein; Daxx; hDaxx; ETS1-associated protein 1; EAP1; Fas death domain-associated protein], [DAXX; DAXX; DAP6; EAP1; BING2; BING2; DAP6; hDaxx; EAP1] |
Gene, Accession # | [DAXX], Gene ID: 1616, NCBI: NP_001135441.1, UniProt: Q9UER7 |
Catalog # | MBS222885 |
Price | $550 |
Order / More Info | Human DAXX Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |