CASP12 (Center), 165-193 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | CASP12 (Center), 165-193 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.39 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This CASP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-193 amino acids from the Central region of human CASP12. Caspases are cysteine proteases that cleave C-terminalaspartic acid residues on their substrate molecules. This gene ismost highly related to members of the ICE subfamily of caspasesthat process inflammatory cytokines. In rodents, the homolog ofthis gene mediates apoptosis in response to endoplasmic reticulumstress. However, in humans this gene contains a polymorphism forthe presence or absence of a premature stop codon. The majority ofhuman individuals have the premature stop codon and produce atruncated non-functional protein. The read-through |
| Immunogen | n/a |
| Other Names | [Inactive caspase-12; CASP-12; CASP12] |
| Gene, Accession # | [CASP12], Gene ID: 100506742, NCBI: NP_001177945.1, UniProt: Q6UXS9 |
| Catalog # | MBS9211511 |
| Price | $165, $370 |
| Order / More Info | CASP12 (Center), 165-193 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Lee, H.J., et al. Arch. Biochem. Biophys. 502(1):68-73(2010) Plantinga, T.S., et al. J. Acquir. Immune Defic. Syndr. 55(1):87-94(2010) McCall, M.B., et al. Eur. Cytokine Netw. 21(2):77-83(2010) Kachapati, K., et al. Hum. Mutat. 27 (9), 975 (2006) : Xue, Y., et al. Am. J. Hum. Genet. 78(4):659-670(2006) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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