Human Interleukin-17 Receptor B (IL17RB) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human Interleukin-17 Receptor B (IL17RB) antibody, protein, ELISA kits.
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| Antigenic Specificity | Human Interleukin-17 Receptor B (IL17RB) |
| Clone | [BFI-7C7] |
| Host Species | Rat |
| Reactive Species | n/a |
| Isotype | IgG2b/kappa |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), ELISA (EIA), C-ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: anti-human IL17RB. Purified monoclonal rat antibody. The IL17RB protein is a cytokine receptor. This receptor specifically binds to IL17B and IL17E (IL25), but does not bind to IL17A or IL17C (1, 2). This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E (3,4). The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. This antibody is recommended for applications under non-denaturing conditions. |
| Immunogen | Immunogen: Genetic immunisation with cDNA encoding the extracellular domain (ecd) of human IL17RB |
| Other Names | [interleukin-17 receptor B; Interleukin-17 receptor B; interleukin-17 receptor B; interleukin 17 receptor B; Cytokine receptor-like 4; IL-17 receptor homolog 1; IL-17Rh1; IL17Rh1; Interleukin-17B receptor; IL-17B receptor], [IL17RB; IL17RB; CRL4; EVI27; IL17BR; IL17RH1; CRL4; EVI27; IL17BR; IL-17 receptor B; IL-17RB; IL-17Rh1; IL17Rh1; IL-17B receptor] |
| Gene, Accession # | [IL17RB], Gene ID: 55540, NCBI: NP_061195.2 |
| Catalog # | MBS468049 |
| Price | $505 |
| Order / More Info | Human Interleukin-17 Receptor B (IL17RB) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Rickel EA et al. (2008). Identification of functional roles for both IL-17RB and IL-17Ra in mediating IL-25-induced activities. J. Immunol. 181(6):4299-4310.2. Reynolds JM et al. (2015). Interleukin-17B antagonizes Interleukin-25-mediated mucosal inflammation. Immunity 42(4):692-703.3. Maezawa Y et al. (2006). Involvement of TNF receptor-associated factor 6 in IL-25 receptor signalling. J. Immunol. 176(2):1013-1018.4. Hata K et al. (2002). IL-17 stimulates inflammatory responses via NF-kappaB and MAP kinase pathways in human colonic myofibroblasts. Am. J. Physiol. Gastrointest. Liver Physiol. 282(6):G1035-1044. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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