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Antigenic Specificity | FGFR2 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. Required for normal embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis and skin development. Plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. Promotes cell proliferation in keratinocytes and immature osteoblasts, but promotes apoptosis in differentiated osteoblasts. Phosphorylates PLCG1, FRS2 and PAK4. Ligand binding leads to the activation of severa |
Immunogen | Immunogen: A synthesized peptide derived from human FGFR2. Subcellular Localization: Cell membrane; Single-pass type I membrane protein. Golgi apparatus. Cytoplasmic vesicle. Detected on osteoblast plasma membrane lipid rafts. After ligand binding, the activated receptor is rapidly internalized and degraded. |
Other Names | [Fibroblast growth factor receptor 2; FGFR-2; 2.7.10.1; K-sam; KGFR; Keratinocyte growth factor receptor; CD332; FGFR2; BEK; KGFR; KSAM], [FGFR2; FGFR2; BEK; JWS; BBDS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM; BEK; KGFR; KSAM; FGFR-2; KGFR] |
Gene, Accession # | [FGFR2], Gene ID: 2263, NCBI: NP_000132.3, UniProt: P21802 |
Catalog # | MBS179209 |
Price | $160, $340, $340 |
Order / More Info | FGFR2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |