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Antigenic Specificity | Phospho-FYN-S21 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance. Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain. Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions. Involved in the regulation of cell adhesion and motility through phosphorylation of CTNNB1 (beta-catenin) and CTNND1 (delta-catenin). Regulates cytoskeletal remodeling by phosphorylating several proteins including the actin regulator WAS and the microt |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding S21 of human FYN |
Other Names | [SLK; SYN; p59-FYN] |
Gene, Accession # | [FYN], Gene ID: 2534, NCBI: NP_002028.1, UniProt: P06241 |
Catalog # | MBS8550637 |
Price | $280 |
Order / More Info | Phospho-FYN-S21 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |