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Antigenic Specificity | STING / TMEM173 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Affinity Purifeid Stimulator of interferon genes protein isoform 1 Antibody. Viral infections stimulate transcription factor including NK-Kb, IRF3 which stimulate the secretion of type I interferon and innate antiviral response. Stimulator of interferon gene protein (STING) is a critical adapter protein that links virus sensing receptor to transcription factor IRF3 activation in response to both RNA and DNA pathogens. The mechanism through wihich interferons are induced by cytosolic DNA involces cyclic GMP-AMP synthase which binds and activates the endoplasmic reticulum adapter protein STING that activates the transcription activity of interferon synthesis. STING recruits and activates the cytosolic kinase IKK and TBK1, which activates the |
Immunogen | Immunogen: Synthetic peptide corresponding to amino acid region 332-342. The selected peptide was post-synthetically modified to achieve highest antigenicity before coupling to a carrier protein using hetero bifunctional cross linker. Immunoglobulin & Concentration: 0.75 mg/mL in antibody stabilization buffer |
Other Names | [endoplasmic reticulum IFN stimulator; ERIS; FLJ38577; Mediator of IRF3 activation; MITA; Mitochondrial mediator of IRF3 activation; MPYS; N terminal methionine proline tyrosine serine plasma membrane tetraspanner; NET23; Stimulator of interferon genes; STING; Tmem173; Transmembrane protein 173], [TMEM173; TMEM173; ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING; ERIS; MITA; STING; hSTING; ERIS; hMITA] |
Gene, Accession # | [STING / TMEM173], Gene ID: 340061, NCBI: NP_938023 |
Catalog # | MBS540684 |
Price | $390 |
Order / More Info | STING / TMEM173 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |