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Antigenic Specificity | Oligophrenin 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Oligophrenin 1 antibody detects endogenous levels of Oligophrenin 1. Function: Stimulates GTP hydrolysis of members of the Rho family. Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function. Critical for the stabilization of AMPA receptors at postsynaptic sites. Critical for the regulation of synaptic vesicle endocytosis at presynaptic terminals. Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation (By similarity).Subunit Structure: Interacts with HOMER1. Interacts with AMPA receptor complexes. Interacts with SH3GL2 (endophilin-A1) (By similarity). Interacts (vi |
Immunogen | Immunogen: A synthesized peptide derived from human Oligophrenin 1. Tissue Specificity: Expressed in brain. Predicted Cross Reactivity: Pig, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (83%), Xenopus (82%) |
Other Names | [ARHGAP41; Mental retardation, X linked 60; MRX60; Oligophrenin 1; Oligophrenin 1, Rho GTPase activating protein; OPN1] |
Gene, Accession # | [OPHN1], Gene ID: 4983, NCBI: NP_002538.1, UniProt: O60890 |
Catalog # | MBS9603662 |
Price | $240, $280 |
Order / More Info | Oligophrenin 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |