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Antigenic Specificity | PARD6A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of 193T cell lines, using PARD6A antibody. Immunohistochemistry of paraffin-embedded human gastric cancer tissue using PARD6A antibody. This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Immunogen | Immunogen: A synthetic peptide of human PRKC |
Other Names | [Pard6a protein; Partitioning defective 6 homolog alpha; partitioning defective 6 homolog alpha; par-6 family cell polarity regulator alpha] |
Gene, Accession # | [PARD6A], Gene ID: 56513, NCBI: AAH61114.1 |
Catalog # | MBS4150231 |
Price | $385 |
Order / More Info | PARD6A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |