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Antigenic Specificity | IL-27 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-27 Antibody: Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naive but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through C |
Immunogen | Immunogen: IL-27 antibody was raised against a 14 amino acid synthetic peptide from near the center of human IL-27. Buffer: IL-27 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [IL-27; p28; IL30; IL-27; IL27A; IL-27A; IL27p28; Interleukin-27 subunit alpha; p28; IL-27 subunit alpha; interleukin 27], [IL27; IL27; p28; IL30; IL-27; IL27A; IL-27A; IL27p28; IL27A; IL30; IL-27 subunit alpha; IL-27-A; IL27-A] |
Gene, Accession # | [IL27], Gene ID: 246778, NCBI: NP_663634, UniProt: Q8NEV9 |
Catalog # | MBS150576 |
Price | $375 |
Order / More Info | IL-27 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |