IL-27 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIL-27
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionIL-27 Antibody: Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naive but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through C
ImmunogenImmunogen: IL-27 antibody was raised against a 14 amino acid synthetic peptide from near the center of human IL-27. Buffer: IL-27 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[IL-27; p28; IL30; IL-27; IL27A; IL-27A; IL27p28; Interleukin-27 subunit alpha; p28; IL-27 subunit alpha; interleukin 27], [IL27; IL27; p28; IL30; IL-27; IL27A; IL-27A; IL27p28; IL27A; IL30; IL-27 subunit alpha; IL-27-A; IL27-A]
Gene, Accession #[IL27], Gene ID: 246778, NCBI: NP_663634, UniProt: Q8NEV9
Catalog #MBS150576
Price$375
Order / More InfoIL-27 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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