NPHS2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNPHS2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration2.8 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total NPHS2 protein. This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined.
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to residues near the C terminal of human nephrosis 2, idiopathic, steroid-resistant
Other Names[PDCN; SRN1]
Gene, Accession #[NPHS2], Gene ID: 7827, NCBI: NP_001284504.1, UniProt: Q9NP85
Catalog #MBS9406921
Price$255
Order / More InfoNPHS2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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