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Antigenic Specificity | NPHS2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 2.8 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total NPHS2 protein. This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to residues near the C terminal of human nephrosis 2, idiopathic, steroid-resistant |
Other Names | [PDCN; SRN1] |
Gene, Accession # | [NPHS2], Gene ID: 7827, NCBI: NP_001284504.1, UniProt: Q9NP85 |
Catalog # | MBS9406921 |
Price | $255 |
Order / More Info | NPHS2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |