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Antigenic Specificity | ITGAV |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Integrins are alpha/beta heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival (1, 2). The integrin family contains at least 18 alpha and 8 beta subunits that form 24 known integrins with distinct tissue distribution and overlaping ligand specificities (3). Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with extracellular environment (inside-out signaling) (1, 2). Several alphaV subfamily members, including alphaVbeta3, alphaVbeta5, alphaVbeta1, are highly expressed in active endothelial cells and cancer cells (3-6) where they play a critical |
Immunogen | Immunogen: A synthetic peptide of human ITGAV Observed Molecular Weight: 115kDa |
Other Names | [CD51; MSK8; VNRA; VTNR] |
Gene, Accession # | [ITGAV], Gene ID: 3685, NCBI: AAI44101.1 |
Catalog # | MBS2523854 |
Price | $150, $225, $360 |
Order / More Info | ITGAV Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |