CSFR (Phospho-Tyr708) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCSFR (Phospho-Tyr708)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe Antibody detects endogenous levels of CSF1R only when phosphorylated at tyrosine 708. Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development. Hampe A., Oncogene Res. 4:9-17(1989).A
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 708 (K-K-Y(p)-V-R) derived from Human CSFR.
Other Names[C-FMS; CD115; CSF1R; FIM2; FMS]
Gene, Accession #[CSFR], Gene ID: 1436, NCBI: NP_001275634.1, UniProt: P07333
Catalog #MBS9404852
Price$200, $255
Order / More InfoCSFR (Phospho-Tyr708) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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