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Antigenic Specificity | CSFR (Phospho-Tyr708) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The Antibody detects endogenous levels of CSF1R only when phosphorylated at tyrosine 708. Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development. Hampe A., Oncogene Res. 4:9-17(1989).A |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 708 (K-K-Y(p)-V-R) derived from Human CSFR. |
Other Names | [C-FMS; CD115; CSF1R; FIM2; FMS] |
Gene, Accession # | [CSFR], Gene ID: 1436, NCBI: NP_001275634.1, UniProt: P07333 |
Catalog # | MBS9404852 |
Price | $200, $255 |
Order / More Info | CSFR (Phospho-Tyr708) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |