Klotho (C-term) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKlotho (C-term)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size0.05 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis Klotho antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 284-315 amino acids from the C-terminal region of human Klotho. May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 239 and 872, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity).
Immunogenn/a
Other Names[Klotho; 3.2.1.31; Klotho peptide; KL]
Gene, Accession #[KL], Gene ID: 9365, NCBI: NP_004786.2, UniProt: Q9UEF7
Catalog #MBS9217294
Price$165, $370
Order / More InfoKlotho (C-term) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesKuro-o M.,et al.Nature 390:45-51 (1997). Matsumura Y.,et al.Biochem. Biophys. Res. Commun. 242:626-630 (1998). Dunham A.,et al.Nature 428:522-528 (2004). Kato Y.,et al.Biochem. Biophys. Res. Commun. 267:597-602 (2000). Yahata K.,et al.J. Mol. Med. 78:389-394 (2000).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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