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Antigenic Specificity | Lamin B Receptor/LBR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Direct ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for Lamin B Receptor/LBR detection. Tested with WB, IHC-P, Direct ELISA in Human; Mouse; Rat.Background: Lamin-B receptor is a protein, and in humans, it is encoded by the LBR gene. It is mapped to 1q42.12. The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protei |
Immunogen | Immunogen: E Coli-derived human Lamin B Receptor/LBR recombinant protein (Position: H102-F209). Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Relevant Detection Systems: Relevant Detection Systems: We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (MBS176460) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (MBS176453) for IHC(P). |
Other Names | [Lamin-B receptor; lamin B receptor; Lamin-B receptor; Integral nuclear envelope inner membrane protein; LMN2R; LBR] |
Gene, Accession # | [LBR], Gene ID: 3930, NCBI: NP_002287.2, UniProt: Q14739 |
Catalog # | MBS1752459 |
Price | $315 |
Order / More Info | Lamin B Receptor/LBR Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Holmer L, Pezhman A, Worman HJ (December 1998). The human lamin B receptor/sterol reductase multigene family. Genomics. 54 (3): 469-76. 2. Schuler E, Lin F, Worman HJ (April 1994). Characterization of the human gene encoding LBR, an integral protein of the nuclear envelope inner membrane. The Journal of Biological Chemistry.269 (15): 11312-7. |