Actin (Tyr-53), Phospho-Specific Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Actin (Tyr-53), Phospho-Specific |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse, chicken |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody detects a 42 kDa* protein corresponding to the molecular mass of Actin on SDS-PAGE immunoblots of pervanadate treated human C2C12 and SYF cSrc transformed cells, but not in control cells. In addition, this antibody either detects actin cleavage products at 36 and 20 kDa, or cross-reacts with unidentified proteins at these molecular weights in C2C12 cells. Actin is a major cytoskeletal protein involved in diverse cellular functions including cell motility, adhesion, and morphology. Six different actin isoforms have been identified in vertebrates. There are four alpha isoforms: skeletal, cardiac, and two smooth muscle (enteric and aortic) actins, along with two cytoplasmic actins (beta and gamma). Actin exists in two principal f |
| Immunogen | Immunogen: Phospho-Actin (Tyr-53) synthetic peptide (coupled to KLH) corresponding to amino acid residues around tyrosine 53 of human beta actin. This sequence is identical to similar regions in all four alpha actins, as well as in gamma actin, and is well conserved in actins from most eukaryotic species. |
| Other Names | [actin, cytoplasmic 1; Actin, cytoplasmic 1; actin, cytoplasmic 1; actin beta; Beta-actin], [ACTB; ACTB; BRWS1; PS1TP5BP1] |
| Gene, Accession # | Gene ID: 60, NCBI: NP_001092.1, UniProt: P60709 |
| Catalog # | MBS474080 |
| Price | $385 |
| Order / More Info | Actin (Tyr-53), Phospho-Specific Antibody from MYBIOSOURCE INC. |
| Product Specific References | Vonach, C. et al. (2011) British J Cancer. 105:263. Jungbluth, A. et al. (1995) FEBS Let. 375:87.Baba, T. et al. (2003) J. Immunol. 170: 3762.Winder, S.J. et al. (2005) J. Cell Sci. 118:651.Liu, X. et al. (2006) Proc Nat Acad Sci U S A. 103(37):13694. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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