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Antigenic Specificity | MMP12 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Macrophage metalloelastase(MMP12) detection. Tested with WB in Human. Background: Matrix metalloproteinase-12(MMP12), also known as MME or ME, is an enzyme that in humans is encoded by the MMP12 gene. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.2. It is though that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. This gene may involved in tissue injury and remodeling. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human MMP12 (428-444aa KIDAVFYSKNKYYYFFQ). |
Other Names | [Macrophage metalloelastase; matrix metallopeptidase 12(macrophage elastase); EC 3.4.24.65; HME; Macrophage elastase; Macrophage metalloelastase; Macrophage metaloelastase; Matrix metallopeptidase 12(macrophage elastase); Matrix metalloprotease 12; Matrix metalloproteinase-12; ME; MGC138506; MME; MMP 12; MMP-12; Mmp12; MMP12_HUMAN], [MMP12; MMP12; ME; HME; MME; MMP-12; HME; MME; ME; hME; MMP-12] |
Gene, Accession # | [MMP12], Gene ID: 4321, NCBI: P39900.1, UniProt: P39900 |
Catalog # | MBS176107 |
Price | $280 |
Order / More Info | MMP12 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |