PDCD6 (Center) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPDCD6 (Center)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis PDCD6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 103-137 amino acids from the Central region of human PDCD6. Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca(2+)- regulated signals along the death pathway (By similarity). Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity. May inhibit KDR/VEGFR2-dependent angiogenesis; the function involves inhibition of VEGF-induced phosphoprylation of the Akt signaling pathway. Seems to play a role in the regulation of the distribution and function of MCOLN1 in t
Immunogenn/a
Other Names[Programmed cell death protein 6; Apoptosis-linked gene 2 protein; Probable calcium-binding protein ALG-2; PDCD6; ALG2]
Gene, Accession #[PDCD6], Gene ID: 10016, NCBI: NP_001254485.1, UniProt: O75340
Catalog #MBS9214299
Price$165, $370
Order / More InfoPDCD6 (Center) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesGanjei J.K.,et al.Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases. Urcelay E.,et al.Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases. Schmutz J.,et al.Nature 431:268-274(2004).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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