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Antigenic Specificity | SYK |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, monkey |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SYK antibody detects endogenous levels of total SYK. Description: Syk is a cytoplasmic tyrosine kinase of the SYK family containing two SH2 domains. Plays a central role in the B cell receptor (BCR) response. An upstream activator of the PI3K, PLCgamma2, and Rac/cdc42 pathways in the BCR response. Required for the sequential events of Fc gamma IIa receptor-mediated phagocytosis. Expression highest in murine spleen, heart, mammary gland and thymus. Two splice variant isoforms have been described.Function: Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes i |
Immunogen | Immunogen: Purified recombinant fragment of human SYK expressed in E. Coli Subcellular Location: Cell Membrane. Cytoplasm, Cytosol. Tissue Specificity: Widely expressed in hematopoietic cells (at protein level). Within the B-cells compartment it is for instance expressed for pro-B-cells to plasma cells. |
Other Names | [EC 2.7.10.2; kinase Syk; KSYK; KSYK_HUMAN; p72-Syk; p72syk; Spleen tyrosine kinase; Syk; Tyrosine protein kinase SYK; Tyrosine-protein kinase SYK] |
Gene, Accession # | [SYK], Gene ID: 6850, NCBI: NP_001128524.1, UniProt: P43405 |
Catalog # | MBS9602354 |
Price | $235, $295, $370 |
Order / More Info | SYK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |