Hsp70 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHsp70
Clone[5A5]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat, amphibians, chicken, fish, Fruit Fly, yeast
IsotypeIgG1
Formatperoxidase (HRP) conjugate
Size0.1 mg
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Antibody Microarray (AM)
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DescriptionDetects ~70kDa. May detect HSP70, HSC70, Grp78 and HSP72. Background: HSP70 genes encode abundant heat-inducible 70-kDa HSPs (HSP70s). In most eukaryotes HSP70 genes exist as part of a multigene family. They are found in most cellular compartments of eukaryotes including nuclei, mitochondria, chloroplasts, the endoplasmic reticulum and the cytosol, as well as in bacteria. The genes show a high degree of conservation, having at least 50% identity (2). The N-terminal two thirds of HSP70s are more conserved than the C-terminal third. HSP70 binds ATP with high affinity and possesses a weak ATPase activity which can be stimulated by binding to unfolded proteins and synthetic peptides (3). When HSC70 (constitutively expressed) present in mammalia
ImmunogenImmunogen: Human recombinant HSP70 overexpressed in E.coli. Cellular Localization: Cytoplasm
Other Names[Hsp70 1; Hsp70 2; Hsp70.1; Hsp72; HSPA1; HSPA1A; HSPA1B], [HSPA1A; HSPA1A; HSP72; HSPA1; HSP70I; HSP70-1; HSP70-1A; HEL-S-103; HSPA1; HSX70HSPA1B; HSP70-1/HSP70-2; HSP70.1/HSP70.2]
Gene, Accession #Gene ID: 3303, NCBI: NP_005336.3, UniProt: P08107
Catalog #MBS804384
Price$405
Order / More InfoHsp70 Antibody from MYBIOSOURCE INC.
Product Specific References1. Balashova N. et al. (2005) J Biol Chem 280:2186-96. 2. Boorstein W. R., Ziegelhoffer T. & Craig E. A. (1993) J. Mol. Evol.38 (1): 1-17. 2. Rothman J. (1989) Cell 59: 591 -601. 3. DeLuca-Flaherty et al. (1990) Cell 62: 875-887. 4. Bork P., Sander C. & Valencia A. (1992) Proc. Nut1 Acad. Sci. USA 89: 7290-7294. 5. Fink A.L. (1999) Physiol. Rev. 79: 425-449.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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