AIM2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | AIM2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.02 mL, 0.06 mL, 0.12 mL |
| Concentration | 3.4mg/mL |
| Applications | ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Interferon-inducible protein AIM2 (Absent in melanoma 2) is a 343 amino acid protein belonging to the HIN-200 family. Induced by IFN-(c), AIM2 is thought to act as a tumor suppressor by repressing NF?B transcriptional activity. Localized to the nucleus, AIM2 contains one DAPIN domain and one HIN-200 domain. The DAPIN domain is composed mostly of a-helixes and is a protein-protein interaction domain capable of binding other DAPIN domains. The HIN-200 domain has been shown to bind directly to DNA, which, along with the binding of another protein ASC, results in the activation of Caspase-1. |
| Immunogen | Immunogen: Recombinant protein of human AIM2 |
| Other Names | [PYHIN4] |
| Gene, Accession # | [AIM2], NCBI: AIC62068.1 |
| Catalog # | MBS2522174 |
| Price | $110, $150, $225 |
| Order / More Info | AIM2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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