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Antigenic Specificity | Cdk5 |
Clone | [1H3] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody is specific for the ~ 28kDa Cdk5 protein in Western blots of rat striatal lysate. The antibody shows no cross reactivity with the Cdk5 cofactor p35 or its degradation product p25. This monoclonal also works well for immunocytochemistry using primary cultured rat neurons and for immunohistochemistry on mouse brain tissue. Mouse monoclonal antibody |
Immunogen | Antigen: Purified rat Cdk5. Immunogen Information: Purified rat Cdk5. Immunogen Species: Rat |
Other Names | [cyclin-dependent kinase 5; Cyclin-dependent kinase 5; cyclin-dependent kinase 5; TPKII catalytic subunit; cell division protein kinase 5; serine/threonine-protein kinase PSSALRE; tau protein kinase II catalytic subunit; cyclin-dependent kinase 5; Cell division protein kinase 5; Serine/threonine-protein kinase PSSALRE; Tau protein kinase II catalytic subunit], [Cdk5; Cdk5; Cdkn5; TPKII catalytic subunit] |
Gene, Accession # | [CDK5], Gene ID: 140908, NCBI: NP_543161.1, UniProt: Q03114 |
Catalog # | MBS500027 |
Price | $360 |
Order / More Info | Cdk5 Antibody from MYBIOSOURCE INC. |
Product Specific References | • Kansy, J. et al. Identification of tyrosine hydroxylase as a physiological substrate of Cdk5. J. Neurochem. 91, 374-384 (2004).• Nguyen, C. & Bibb, J. A. Cdk5 and the mystery of synaptic vesicle endocytosis. J Cell Biol. 163, 697- 699 (2003).• Bibb, J. A. et al. Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signaling in neurons. Nature 402, 669-671 (1999).• Lagace, D. C. et al. Cdk5 is essential for adult hippocampal neurogenesis. Proc Natl Acad Sci USA 105, 18567-18571 (2008). |