Caveolin 2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCaveolin 2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: Caveolin 2 antibody detects endogenous levels of total Caveolin 2. Function: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity).Subunit Structure: Monomer or homodimer. Interacts with CAV1;
ImmunogenImmunogen: A synthesized peptide derived from human Caveolin 2 Subcellular Location: Nucleus. Cytoplasm. Golgi Apparatus Membrane. Cell Membrane. Membrane > Caveola. Potential hairpin-like structure in the membrane. Membrane protein of caveolae. Tyr-19-phosphorylated form is enriched at sites of cell-cell contact and is translocated to the nucleus in complex with MAPK1 in response to insulin (By similarity). Tyr-27-phosphorylated form is located both in the cytoplasm and plasma membrane. CAV1-me
Other Names[CAV; CAV2; CAV2_HUMAN; Caveolae protein 20 kD; Caveolin 2; Caveolin 2 isoform a and b; Caveolin-2; MGC12294; OTTHUMP00000025032; OTTHUMP00000195982]
Gene, Accession #[CAV2], Gene ID: 858, NCBI: NP_001193676.1, UniProt: P51636
Catalog #MBS9601580
Price$240, $280
Order / More InfoCaveolin 2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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