PCSK9 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPCSK9
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat, mouse, gorilla
Isotypen/a
Formatepitope affinity purified
Size0.1 mg
ConcentrationSize: 100 ug/200 ul
ApplicationsELISA, Western Blot, Immunohistochemistry
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DescriptionThis antibody recognizes ~74 kDa of human PCSK9 protein. It also reacts with mouse and rat. The other species are not tested. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a member of the serine protease family with a critical role in cholesterol metabolism by controlling the levels of low density lipoprotein (LDL) particles that circulate in the bloodstream. Mutation in the PCSK9 gene is associated with autosomal dominant hypercholesterolemia which is characterized by an increase in LDL cholesterol levels. PCSK9 is expressed in various tissues such as liver, kidney, lung, spleen, etc. Human PCSK9 precursor is 692 aa protein with 74kDa molecular weight. Its mature form has molecular weight ranging of 62-66 kDa in the tissues.
ImmunogenAntigen Preparation: A synthetic peptide derived from 100aa-300aa of Human PCSK9 protein. This sequence is identical among human, rat, mouse, gorilla, etc.
Other Names[Rabbit PCSK9; Proprotein convertase subtilisin/kexin type 9 (PCSK9) Proprotein concertase PC9; Subtilisin/Kexin-like protease PC9; FH3; NARC1], [PCSK9; PCSK9; FH3; PC9; NARC1; LDLCQ1; NARC-1; HCHOLA3; NARC1]
Gene, Accession #[PCSK9], Gene ID: 255738, NCBI: NP_777596.2, UniProt: Q8NBP7
Catalog #MBS462174
Price$285
Order / More InfoPCSK9 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLopez D (2008) PCSK9: an enigmatic protease. Biochim Biophys Acta. 1781 (4): 184-91.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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