PAK3 (Center K218), 218-247 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PAK3 (Center K218), 218-247 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 1.64 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This PAK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-247 amino acids from the Central region of human PAK3. PAK3, a member of the STE20 subfamily of Ser/Thr protein kinases, acts on a variety of targets. PAK3 interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1. It shows highly specific binding to the SH3 domains of phospholipase C-gamma and of adapter protein NCK. This protein is highly expressed in postmitotic neurons of the developing and postnatal cerebral cortex and hippocampus. PAK3 is autophosphorylated when activated by CDC42/p21. Defects in PAK3 are the cause of non-specific X-linked nonsyndromic mental retardation type 30 (MRX30). The protein structure contains |
| Immunogen | n/a |
| Other Names | [Serine/threonine-protein kinase PAK 3; Beta-PAK; Oligophrenin-3; p21-activated kinase 3; PAK-3; PAK3; OPHN3] |
| Gene, Accession # | [PAK3], Gene ID: 5063, NCBI: NP_001121638.1, UniProt: O75914 |
| Catalog # | MBS9212335 |
| Price | $165, $370 |
| Order / More Info | PAK3 (Center K218), 218-247 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Kitano, T., et al., Mol. Biol. Evol. 20(8):1281-1289 (2003). Allen, K.M., et al., Nat. Genet. 20(1):25-30 (1998). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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