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Antigenic Specificity | Phospho-SHP2 (Y542) |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity. |
Immunogen | Immunogen: A synthesized peptide derived from human Phospho-SHP2 (Y542) Subcellular Localization: Cytoplasm. Tissue Specificity: Widely expressed, with highest levels in heart, brain, and skeletal muscle. |
Other Names | [Tyrosine-protein phosphatase non-receptor type 11; 3.1.3.48; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3; PTPN11; PTP2C; SHPTP2] |
Gene, Accession # | [SHP2], Gene ID: 5781, NCBI: NP_001317366.1, UniProt: Q06124 |
Catalog # | MBS1750213 |
Price | $160, $340, $340 |
Order / More Info | Phospho-SHP2 (Y542) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |