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Antigenic Specificity | NTRK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 3.2 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total NTRK1 protein. This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to residues near the C terminal of human neurotrophic tyrosine kinase, receptor, type 1 |
Other Names | [MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA] |
Gene, Accession # | [NTRK1], Gene ID: 4914, NCBI: NP_001007793.1, UniProt: P04629 |
Catalog # | MBS9409747 |
Price | $255 |
Order / More Info | NTRK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |