AIFM1 (N-term), 70-98 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | AIFM1 (N-term), 70-98 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This AIFM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 amino acids from the N-terminal region of human AIFM1. AIFM1 is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this protein induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. |
| Immunogen | n/a |
| Other Names | [Apoptosis-inducing factor 1; mitochondrial; 111-; Programmed cell death protein 8; AIFM1; AIF; PDCD8] |
| Gene, Accession # | [AIFM1], Gene ID: 9131, NCBI: NP_001124318.1, UniProt: O95831 |
| Catalog # | MBS9201935 |
| Price | $165, $370 |
| Order / More Info | AIFM1 (N-term), 70-98 Antibody from MYBIOSOURCE INC. |
| Product Specific References | References for protein: 1.Daugas,E., et.al., FASEB J. 14 (5), 729-739 (2000) 2.Schulthess,F.T., et.al., PLoS ONE 4 (2), E4394 (2009) References for U251 cell line: 1. Westermark B.; Ponten J.; Hugosson R. (1973). Determinants for the establishment of permanent tissue culture lines from human gliomas. Acta Pathol Microbiol Scand A. 81:791-805. [PMID: 4359449]. 2. Ponten, J.,Westermark B. (1978). Properties of Human Malignant Glioma Cells in Vitro. Medical Biology 56: 184-193.[PMID: 359950]. 3. Geng Y.;Kohli L.; Klocke B.J.; Roth K.A.(2010). Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent. Neuro Oncol. 12(5): 473-481.[ PMID: 20406898]. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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