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Antigenic Specificity | CaVbeta3 Subunit |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL |
Concentration | 1ug/ul |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Rat, mouse, human, Xenopus-identical; bovine-14/15 residues identical. The b3 protein is an auxiliary subunit of the CaV (voltage dependent calcium) channel multimer complex. Four b isoforms were identified in mammalian genoms and they share some sequence as well as structure homology.1-3 The structure of CaVb3 was recentely determined (as well as other CaVb subunits; for review see reference 3). CaVb subunits are cytoplasmic proteins, that bind the cytoplasmic face of the pore forming CaV a1 subunits. These interactions have profound effects on channel trafficing to the plasma membrane as well as on current parameters such as voltage dependent kinetics and interactions with modulatory proteins.1, 2 CaVb3 might interact with al |
Immunogen | Immunogen: Peptide (C)DRNW QRNRP WPKDS Y, corresponding to residues 463-477 of rabbit Cab3 (Accession number P54286). |
Other Names | [Ca2+ Channels] |
Gene, Accession # | [CaVbeta3] |
Catalog # | MBS4159135 |
Price | $725 |
Order / More Info | CaVbeta3 Subunit Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |