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Antigenic Specificity | 14-3-3 ETA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, chicken, human, mammals (expected from sequence), mouse, rabbit, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item recognises 14-3-3 eta in all mammals. It is a member of the 14-3-3 family which consists of 30 kDa proteins that are involved in multiple protein kinase signalling pathways, regulation of cell cycle progression, cytoskeletal structure, transcription, intracellular trafficking and targeting. Protein interactions with 14-3-3 show distinct preference for it's different isoforms and are regulated by phosphorylation of both 14-3-3 and the bound protein.. . 14-3-3 eta is expressed principally in the brain although it is expressed at low levels in other tissues. The protein binds alpha-synuclein, forming part of lewy bodies in parkinsons disease and has been linked to early-onset schizophrenia. The eta isoform binds both gremlin 1, whi |
Immunogen | Immunogen: Synthetic peptide corresponding to acetylated N-terminal sequence of sheep 14-3-3 eta. Peptide sequence: Ac.GDREQLLQRARC Histology Positive Control Tissue: Normal brain tissue Antiserum Preparation: Antisera to sheep 14-3-3 eta were raised by repeated immunisations of rabbit with highly purified antigen. Target Species: Sheep |
Other Names | [14-3-3 protein eta; 14-3-3 protein eta; 14-3-3 protein eta; 14-3-3 eta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta; Protein AS1], [YWHAH; YWHAH; YWHA1; YWHA1] |
Gene, Accession # | [14-3-3 ETA], Gene ID: 7533, NCBI: NP_003396.1 |
Catalog # | MBS222331 |
Price | $375 |
Order / More Info | 14-3-3 ETA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |