NF-kappaB p65 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | NF-kappaB p65 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat, zebrafish |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: NF-kappaB p65 antibody detects endogenous levels of total NF-kappaB p65. Description: NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex. The p50 (NFKB1)/p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NFKB by trapping it in the cytoplasm.Function: NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, |
| Immunogen | Immunogen: A synthesized peptide derived from human NF-kappaB p65 Subcellular Location: Nucleus. Cytoplasm. Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor (I-kappa-B). Colocalized with RELA in the nucleus upon TNF-alpha induction. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Dog Similarity: Pig (100%), Bovine (91%), Horse (91%), Sheep (91%), Dog (100%) |
| Other Names | [Avian reticuloendotheliosis viral (v rel) oncogene homolog A; MGC131774; NF kappa B p65delta3; NFKB3; Nuclear Factor NF Kappa B p65 Subunit; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 3; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; OTTHUMP00000233473; OTTHUMP00000233474; OTTHUMP00000233475; OTTHUMP00000233476; OTTHUMP00000233900; p65; p65 NF kappaB; p65 NFkB; relA; TF65_HUMAN; Transcription factor p65; v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65)); V rel avian reticuloendotheliosis viral oncogene homolog A; v rel reticuloendotheliosis viral oncogene homolog A (avian); V rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B cells 3, p65] |
| Gene, Accession # | [RELA], Gene ID: 5970, NCBI: NP_001138610.1, UniProt: Q04206 |
| Catalog # | MBS9601268 |
| Price | $240, $280 |
| Order / More Info | NF-kappaB p65 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Zhu L, Xu H, Lv W, He Z, Ye P, Wang Y, Hu J; Journal: Inflammation. miR-199b-5p Regulates Immune-Mediated Allograft Rejection after Lung Transplantation Through the GSK3beta and NF-kB Pathways. Yu D, Ye X, Che R, Wu Q, Qi J, Song L, Guo X, Zhang S, Wu H, Ren G, Li D; Journal: Biomed Pharmacother. FGF21 exerts comparable pharmacological efficacy with Adalimumab in ameliorating collagen-induced rheumatoid arthritis by regulating systematic inflammatory response. Zheng L, Feng L, Jiang WD, Wu P, Tang L, Kuang SY, Zeng YY, Zhou XQ, Liu Y; Journal: Fish Shellfish Immunol. Selenium deficiency impaired immune function of the immune organs in young grass carp (Ctenopharyngodon idella). Wu Q, Wang Y, Wang Q, Yu D, Wang Y, Song L, Liu Z, Ye X, Xu P, Cao H, Li D, Ren G; Journal: Immunol Lett. The bispecific antibody aimed at the vicious circle of IL-1beta and IL-17A, is beneficial for the collagen-induced rheumatoid arthritis of mice through NF-kB signaling pathway. Yu Y, Li S, Liu Y, Tian G, Yuan Q, Bai F, Wang W, Zhang Z, Ren G, Zhang Y, Li D; Journal: Int Immunopharmacol. Fibroblast growth factor 21 (FGF21) ameliorates collagen-induced arthritis through modulating oxidative stress and suppressing nuclear factor-kappa B pathway. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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