Phospho-RB1-S780 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-RB1-S780
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
ImmunogenImmunogen: A phospho specific peptide corresponding to residues surrounding S780 of human RB1 Calculated Molecular Weight: 110kDa
Other Names[Phospho-RB1-S780: RB; pRb; OSRC; pp110; p105-Rb], [RB1; RB1; RB; pRb; OSRC; pp110; p105-Rb; PPP1R130; Rb]
Gene, Accession #[RB1], Gene ID: 5925, NCBI: P06400.2, UniProt: P06400
Catalog #MBS128502
Price$235, $350, $525
Order / More InfoPhospho-RB1-S780 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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