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Antigenic Specificity | Integrin alpha 4 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha- 4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha- 4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells. |
Immunogen | Immunogen: A synthesized peptide derived from human Integrin alpha 4. Subcellular Localization: Membrane; Single-pass type I membrane protein. |
Other Names | [Integrin alpha-4; CD49 antigen-like family member D; Integrin alpha-IV; VLA-4 subunit alpha; CD49d; ITGA4; CD49D], [ITGA4; ITGA4; IA4; CD49D; CD49D] |
Gene, Accession # | [ITGA4], Gene ID: 3676, NCBI: NP_000876.3, UniProt: P13612 |
Catalog # | MBS179337 |
Price | $160, $340, $340 |
Order / More Info | Integrin alpha 4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |