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Antigenic Specificity | RAD51C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Essential for the homologous recombination (HR) pathway of DNA repair. Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Part of the RAD21 paralog protein complexes BCDX2 and CX3 which act at different stages of the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 seems to act downstream of BRCA2 recruitment and upstream of RAD51 recruitment; CX3 seems to act downstream of RAD51 recruitment; both complexes bind predominantly to the intersection of the four duplex arms of the Holliday junction (HJ) and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps i |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human RAD51C (NP 002867.1). |
Other Names | [FANCO; R51H3; BROVCA3; RAD51L2] |
Gene, Accession # | [RAD51C], Gene ID: 5889, NCBI: NP_002867.1, UniProt: O43502 |
Catalog # | MBS8548689 |
Price | $280 |
Order / More Info | RAD51C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |