ATG14 - middle region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ATG14 - middle region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1. Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine. Promotes BECN1 translocation from the trans-Golgi network to autophagosomes. Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1. Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation PIK3C3 by AMPK. Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to promote autophagosome-endolysosome fusion. Modulates the hepatic lipid metabolism. |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ATG14 |
| Other Names | [beclin 1-associated autophagy-related key regulator; Beclin 1-associated autophagy-related key regulator; beclin 1-associated autophagy-related key regulator; autophagy related 14; Autophagy-related protein 14-like protein; Atg14L] |
| Gene, Accession # | [ATG14], Gene ID: 22863, NCBI: NP_055739.2, UniProt: Q6ZNE5 |
| Catalog # | MBS3221701 |
| Price | $335 |
| Order / More Info | ATG14 - middle region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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