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Antigenic Specificity | TRADD (Center), 126-151 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.36 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TRADD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-151 amino acids from the Central region of human TRADD. The protein encoded by this gene is a death domaincontaining adaptor molecule that interacts with TNFRSF1A/TNFR1 andmediates programmed cell death signaling and NF-kappaB activation.This protein binds adaptor protein TRAF2, reduces the recruitmentof inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thussuppresses TRAF2 mediated apoptosis. This protein can also interactwith receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and isinvolved in the Fas-induced cell death pathway. [provided byRefSeq]. |
Immunogen | n/a |
Other Names | [Tumor necrosis factor receptor type 1-associated DEATH domain protein; TNFR1-associated DEATH domain protein; TNFRSF1A-associated via death domain; TRADD] |
Gene, Accession # | [TRADD], Gene ID: 8717, NCBI: NP_003780.1, UniProt: Q15628 |
Catalog # | MBS9205433 |
Price | $165, $370 |
Order / More Info | TRADD (Center), 126-151 Antibody from MYBIOSOURCE INC. |
Product Specific References | Pointon, J.J., et al. Ann. Rheum. Dis. 69(6):1243-1246(2010) Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009) Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009) Liang, X.S., et al. Br. J. Haematol. 146(4):418-423(2009) Dagle, J.M., et al. Pediatrics 123(4):1116-1123(2009) |