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Antigenic Specificity | APRIL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for a proliferation-inducing ligand), TALL-2 (for TNF- and ApoL-related Leukocyte-expressed Ligand 2), and TRDL-1a (for TNF related death ligand 1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a synthetic peptide corresponding to amino acids near the center of human APRIL. |
Other Names | [tumor necrosis factor ligand superfamily member 13 isoform alpha proprotein; Tumor necrosis factor ligand superfamily member 13; tumor necrosis factor ligand superfamily member 13; tumor necrosis factor (ligand) superfamily, member 13; A proliferation-inducing ligand; APRIL; TNF- and APOL-related leukocyte expressed ligand 2; TALL-2; TNF-related death ligand 1; TRDL-1; CD_antigen: CD256] |
Gene, Accession # | [APRIL], Gene ID: 8741, NCBI: NP_003799 |
Catalog # | MBS9410190 |
Price | $320 |
Order / More Info | APRIL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |