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Antigenic Specificity | HIST3H2A (N-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This HIST3H2A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 33-67 amino acids from the N-terminal region of human HIST3H2A. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Immunogen | n/a |
Other Names | [Purified Rabbit (Pab); Histone H2A type 3; HIST3H2A] |
Gene, Accession # | [HIST3H2A], Gene ID: 92815, NCBI: NP_254280.1, UniProt: Q7L7L0 |
Catalog # | MBS9216388 |
Price | $150 |
Order / More Info | HIST3H2A (N-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Marzluff W.F.,et al.Genomics 80:487-498(2002).Ota T.,et al.Nat. Genet. 36:40-45(2004).Gregory S.G.,et al.Nature 441:315-321(2006).Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.Aihara H.,et al.Genes Dev. 18:877-888(2004). |