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Antigenic Specificity | Calnexin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, bovine, chicken, dog, Drosophila, guinea pig, hamster, monkey, porcine, quail, rabbit, sheep, Xenopus |
Isotype | n/a |
Format | Protein A purified |
Size | 0.05 mg, 0.2 mg |
Concentration | n/a |
Applications | Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Immunoprecipitation (IP), Western Blot (WB), Electron Microscopy |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human, mouse, rat, bovine, dog, chicken, Drosophila, guinea pig, hamster, monkey, pig, quail, rabbit, sheep and Xenopus Calnexin. Detects a band of ~90kDa by Western blot. Calnexin (CNX), an unglycosylated resident ER transmembrane protein, together with Calreticulin (CRT), plays a key role in glycoprotein folding and its control within the ER, by interacting with folding intermediates via their monoglucosylated glycans. Calnexin associates with newly synthesized monomeric glycoproteins and only recognizes glycoproteins when they are incompletely folded. Furthermore, Calnexin has been demonstrated to function as a molecular chaperone capable of interacting with polypeptide segments of folding glycoproteins. |
Immunogen | Immunogen: Synthetic peptide corresponding to the sequence near the C-terminus of dog calnexin. The sequence is completely conserved in human, mouse and rat. |
Other Names | [Calnexin; Calnexin; calnexin; pp90], [CANX; CANX; PP90] |
Gene, Accession # | [CNX], Gene ID: 403908, NCBI: P24643.3, UniProt: P24643 |
Catalog # | MBS565238 |
Price | $290, $500 |
Order / More Info | Calnexin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |