RBCK1 (UBCE7IP3) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RBCK1 (UBCE7IP3) |
| Clone | [1839CT718.19.54] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1,k |
| Format | unconjugated |
| Size | 0.05 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This RBCK1 (UBCE7IP3) antibody is generated from a mouse immunized with a recombinant protein of human RBCK1 (UBCE7IP3). E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2L3/UBCM4, and then transfers it to substrates. Functions as an E3 ligase for oxidized IREB2 and both heme and oxygen are necessary for IREB2 ubiquitination. Promotes ubiquitination of TAB2 and IRF3 and their degradation by the proteasome. Component of the LUBAC complex which conjugates linear ('Met-1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of th |
| Immunogen | n/a |
| Other Names | [RanBP-type and C3HC4-type zinc finger-containing protein 1; 6.3.2.-; HBV-associated factor 4; Heme-oxidized IRP2 ubiquitin ligase 1; HOIL-1; Hepatitis B virus X-associated protein 4; RING finger protein 54; Ubiquitin-conjugating enzyme 7-interacting protein 3; RBCK1; C20orf18; RNF54; UBCE7IP3; XAP3; XAP4] |
| Gene, Accession # | [RBCK1], Gene ID: 10616, NCBI: NP_006453.1, UniProt: Q9BYM8 |
| Catalog # | MBS9230991 |
| Price | $165, $370 |
| Order / More Info | RBCK1 (UBCE7IP3) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Cong Y.-S.,et al.J. Biol. Chem. 272:16482-16489 (1997). Yamanaka K.,et al.Nat. Cell Biol. 5:336-340 (2003). Deloukas P.,et al.Nature 414:865-871 (2001). Hillman R.T.,et al.Genome Biol. 5:R8.1-R8.16 (2004). Zhang Y.,et al.Mol. Cell. Proteomics 4:1240-1250 (2005). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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