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Antigenic Specificity | Phospho-HIST1H3B-T12 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Modulation of chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of DNA wound around eight core histone proteins (two each of H2A, H2B, H3, and H4), is the primary building block of chromatin (1). The amino-terminal tails of core histones undergo various post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination (2-5). These modifications occur in response to various stimuli and have a direct effect on the accessibility of chromatin to transcription factors and, therefore, gene expression (6). In most species, histone H2B is primarily acetylated at Lys5, 12, 15, and 20 (4,7). Histone H3 is primarily acetylated at Lys9, 14, 18, 2 |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding T12 of human HIST1H3B |
Other Names | [Phospho-HIST1H3B-T12: H3/l; H3FL; HIST1H3B], [HIST1H3J; HIST1H3A; H3/j; H3FJ; H3FA] |
Gene, Accession # | [HIST1H3B], Gene ID: 8356, NCBI: P68431.2, UniProt: P68431 |
Catalog # | MBS126207 |
Price | $235, $350, $525 |
Order / More Info | Phospho-HIST1H3B-T12 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |