CD42b Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD42b
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: CD42b antibody detects endogenous levels of total CD42b. Function: GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium.Subunit Structure: Two GP-Ib beta are disulfide-linked to one GP-Ib alpha. GP-IX is complexed with the GP-Ib heterodimer via a non covalent linkage (PubMed:17008541, PubMed:2070794). Interacts with FLNB (PubMed:9651345). Interacts with FLNA (via filamin repeats 4, 9, 12, 17, 19, 21, and 23) (PubMed:19828450).Post-translational Modifications: Glycocalicin, which is approximately coextensive with the extracellular part of the molecule, is cleaved off by calpain during platelet lysis
ImmunogenImmunogen: A synthesized peptide derived from human CD42b Subcellular Location: Cell Membrane Predicted Cross Reactivity: Bovine, Rabbit, Dog Similarity: Bovine (83%), Rabbit (83%), Dog (92%)
Other Names[Antigen CD42b alpha; BDPLT1; BDPLT3; BSS; CD 42b; CD42b alpha; CD42B; CD42b antigen; DBPLT3; GLYCOCALICIN; Glycoprotein Ib (platelet) alpha polypeptide; Glycoprotein Ibalpha; GP Ib alpha; GP1B; GP1BA; GPIb alpha; GPIbA; MGC34595; Platelet glycoprotein Ib alpha chain; Platelet glycoprotein Ib alpha polypeptide; Platelet membrane glycoprotein 1b alpha subunit; VWDP]
Gene, Accession #[CD42b], Gene ID: 2811, NCBI: NP_000164.5, UniProt: P07359
Catalog #MBS9608837
Price$240, $280
Order / More InfoCD42b Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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