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Antigenic Specificity | SMAD2 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces th |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SMAD2 |
Other Names | [mothers against decapentaplegic homolog 2 isoform 1; Mothers against decapentaplegic homolog 2; mothers against decapentaplegic homolog 2; SMAD family member 2; JV18-1; Mad-related protein 2; hMAD-2; SMAD family member 2] |
Gene, Accession # | [SMAD2], Gene ID: 4087, NCBI: NP_001003652.1, UniProt: Q15796 |
Catalog # | MBS3223097 |
Price | $335 |
Order / More Info | SMAD2 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |