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Antigenic Specificity | Human IRAK2 / IRAK-2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Peptide corresponding to 17 amino acids near the carboxy-terminus of mouse IRAK2a which is common to all four isoforms. IRAK2, an IRAK type protein kinase, is a signal transducer for the immune response interleukin-1 receptor (IL-1R) signaling cascade. IRAK2 also has been associated with signaling cell death, potentially via the Fas-associated death domain protein/caspase-8 apoptotic pathway. Dominant negative forms of IRAK2 attenuate IL-1R-mediated NF-kappa B activation, suggesting that IRAK-2 may serve as a therapeutic target for inhibiting IL-1-induced inflammation. |
Immunogen | Immunogen Description: Synthetic peptide from human IRAK2. |
Other Names | [IRAK2 / IRAK-2 (C-Terminus) IHC-plus; IRAK2; Il1rak2; IRAK-2; Human IRAK2; IRAK-2], [IRAK-2] |
Gene, Accession # | [IRAK2], Gene ID: 3656, NCBI: NP_001561.3, UniProt: O43187 |
Catalog # | MBS244266 |
Price | $660 |
Order / More Info | Human IRAK2 / IRAK-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |