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Antigenic Specificity | IL-36R |
Clone | [ABM47A2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-36R is a member of the IL-1 receptor family that has been associated with various inflammation-associated diseases. Ligands binding to IL-36R subsequently recruit the IL-1RAcP (IL-1 Receptor Accessory Protein) forming a heterodimeric signaling complex. The latter is also used by IL-1Alpha and IL-1Beta. IL-36R is expressed by different immune cells, including Dendritic Cells, microglia and other myeloid cells. IL-36 stimulation of DC leads to the production of several cytokines by DC, including TNF-a, IL-1, IL-12, and IL-23. This interaction also enhances the expression of MHC class 2 and co-stimulatory molecules. |
Immunogen | Immunogen Information: A partial length recombinant IL-36R protein (amino acids 1-203) was used as the immunogen for this antibody. |
Other Names | [IL1RL2; IL1RRP2; IL-36 receptor; IL-1Rrp2; Interleukin-1 receptor-related protein 2; to IL-36R; IL-36R; IL-36R], [IL1RL2; IL1RL2; IL-36R; IL1RRP2; IL-1Rrp2; IL1R-rp2; IL1RRP2; IL-36R; IL-1Rrp2; IL1R-rp2] |
Gene, Accession # | [IL-36R], Gene ID: 8808, NCBI: Q9HB29.2, UniProt: Q9HB29 |
Catalog # | MBS668412 |
Price | $290 |
Order / More Info | IL-36R Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |