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Antigenic Specificity | CD43 |
Clone | [MT1] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 5 Control Slides, 3 ml (Prediluted), 0.1 mL (Concentrate) |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD43 (leukosialin, sialophorin, or leukocyte sialoglycoprotein) is one of the major glycoproteins expressed in all thymocytes and T-cells. It plays a role in the physicochemical properties of the T-cell surface and in lectin binding. During T-cell activation, CD43 is actively removed from the T-cell antigen-presenting cell contact site, suggesting a negative regulatory role in adaptive immune response. This antibody has been found useful in identification and classification of T-cell malignancies and low grade B-cell Lymphomas. CD43 expression is seen in some cases of B-cell Lymphocytic Lymphoma and Centrocytic Lymphoma. When used in combination with CD45 and CD20, effective immunophenotyping of the majority of Lymphomas can be obtained. Co |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | [CD43] |
Catalog # | MBS370030 |
Price | $130, $165, $195 |
Order / More Info | CD43 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |