PIK3CD Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PIK3CD |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: PIK3CD antibody detects endogenous levels of total PIK3CD. Function: Phosphoinositide-3-kinase (PI3K) that phosphorylates PftdIns(4, 5)P2 (Phosphatidylinositol 4, 5-bisphosphate) to generate phosphatidylinositol 3, 4, 5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Mediates immune responses. Plays a role in B-cell development, proliferation, migration, and function. Required for B-cell receptor (BCR) signaling. Mediates B-cell proliferation response to anti-IgM, anti-CD40 and IL4 stimulation. Promotes cytokine production in response to TLR4 |
| Immunogen | Immunogen: A synthesized peptide derived from human PIK3CD Tissue Specificity: Isoform 2 is expressed in normal thymus, lung and spleen tissues, and is detected at low levels in normal lysates from colon and ovarian biopsies, at elevated levels in lysates from colorectal tumors and is abundantly expressed in some ovarian tumors (at protein level). Both isoform 1 and isoform 2 are widely expressed. Isoform 1 is expressed predominantly in leukocytes. |
| Other Names | [5-bisphosphate 3-kinase 110 kDa catalytic subunit delta; 5-bisphosphate 3-kinase catalytic subunit delta isoform; APDS; GRB1; IMD14; p110d; p110delta; p110dp85a; p85-ALPHA; Phosphatidylinositol 3 kinase catalytic delta polypeptide; Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit delta isoform; Phosphatidylinositol 4, 5 bisphosphate 3 kinase 110 kDa catalytic subunit delta; Phosphatidylinositol 4, 5 bisphosphate 3 kinase, catalytic subunit delta; Phosphatidylinositol 45 bisphosphate 3 kinase catalytic subunit delta isoform; Phosphatidylinositol-4; Phosphoinositide 3 kinase B; Phosphoinositide 3 kinase C; Phosphoinositide 3 kinase catalytic delta polypeptide; Phosphoinositide 3 kinase, catalytic, delta polypeptide variant p37delta; PI3 kinase p110 subunit delta; PI3-kinase subunit delta; PI3K; PI3K-delta; PI3Kdelta; Pik3cd; PIK3R1; PK3CD; PK3CD_HUMAN; PtdIns 3 kinase p110; PtdIns 3 kinase subunit p110 delta; PtdIns-3-kinase subunit delta; PtdIns-3-kinase subunit p110-delta] |
| Gene, Accession # | [PIK3CD], Gene ID: 5293, NCBI: NP_005017.3, UniProt: O00329 |
| Catalog # | MBS9608216 |
| Price | $240, $280 |
| Order / More Info | PIK3CD Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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